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Advancements in technology have led to the development of promising screening tools, such as liquid biopsies. Liquid biopsies involve analyzing circulating tumor DNA (ctDNA) and other biomarkers in the blood to detect early-stage Non-Small Cell Lung Cancer. This non-invasive approach holds significant potential for early detection, monitoring treatment response, and detecting minimal residual disease. However, further research is needed to validate its efficacy and cost-effectiveness.
Despite the progress made in early detection and screening of Non-Small Cell Lung Cancer, several challenges remain. False-positive results, overdiagnosis, and potential harms associated with invasive follow-up procedures are significant concerns. Additionally, ensuring accessibility and adherence to screening programs among high-risk populations is essential. Future directions should focus on refining risk stratification models, optimizing screening intervals, and integrating emerging technologies to improve the accuracy and cost-effectiveness of NSCLC screening programs.
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