Transdermal drug delivery is a method of drug delivery through the skin, by using patches or devices that are applied to the skin, which allows the drugs to be gradually absorbed into the bloodstream through the dermis and epidermis. TDDS has become a popular alternative to traditional drug delivery methods, such as injections and oral administration.
What Are Advantages of Transdermal Drug Delivery Systems?
Transdermal drug delivery systems offer many advantages over traditional drug delivery methods, such as:
• Improved patient compliance: TDDS eliminates the discomfort related to injections and reduces the need for frequent dosing. This can reduce the possibility of prolonged hospital stays and improve patient compliance.
• Controlled drug delivery: TDDS controls the rate of drug delivery, ensuring a consistent drug level in the bloodstream. This improves patient outcomes and reduces the cost of healthcare.
• Smart delivery of drug: TDDS also offers targeted drug delivery, as the drug is delivered into a specific targeted area of the body, such as a muscle or organ. This reduces the amount of drug required for therapeutic efficacy.
• Avoidance of first-pass metabolism: TDDS eliminate first-pass metabolism, which decreases the amount of drug lost in the gastrointestinal tract, by providing a steady blood concentration of the drugs.
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Applications of Transdermal Drug Delivery Systems
Transdermal drug delivery systems have numerous applications in the medical field, some of which are:
• Pain management: TDDS is used to administer pain medication, for example, buprenorphine patches, which contain medication that provides effective relief from pain.
• Smoking cessation: The number of people smoking is increasing day by day, same as incidence of the illnesses causes by it. So, for people who want to quit smoking, a transdermal nicotine patch is a way to go. These patches are to be applied directly to your skin once a day, and they also reduce withdrawal symptoms.
• Hypertension: High blood pressure (hypertension) is one of the largest death-causing illnesses. A clonidine patch is used to control high blood pressure.
• Motion sickness: TDDS is used to deliver scopolamine to avert motion sickness and prevent nausea and vomiting after surgery, sedative pain medicine, and anesthesia.
• Hormone replacement therapy: Transdermal skin patches, such as those containing climara, alora, minivelle, and dotti are used in a hormone delivery system to patients.
In conclusion, transdermal drug delivery systems offer numerous advantages over traditional drug delivery methods and have several applications in the medical field. TDDS offers a convenient and effective process of medication delivery, preventing the risks and discomfort related to injections or oral administration.
Moreover, the advancement in this field will make TDDS a safer and more-effective way of drug delivery, opening up new ways for treating various diseases and conditions.
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